Villanova University's Department of Chemistry is holding a PDS - Graduate Symposium on November 12, 2013

VILLANOVA UNIVERSITY

Department of Chemistry

 

PDS – GRADUATE SYMPOSIUM

Synergistic Induction of Cytoprotective Heme Oxygenase-1 by  

Co-treating with Sulforaphane and Copper Ions

Zachary Kemmerer

Advisor: Dr. Aimee Eggler

 Oxidative stress is a key component in the development of many chronic diseases, including Alzheimer’s, cardiovascular diseases, and carcinogenesis. Heme oxygenase-1 (HO-1) is a highly inducible cytoprotective protein that produces the antioxidant, bilirubin. Bilirubin is the most potent antioxidant in mammalian serum, and thus is critical for mitigating oxidative stress and inflammation. Small molecule electrophiles and metals have independently been shown to induce HO-1. We hypothesized co-treatment could generate more-than-additive, synergistic induction of HO-1. We find that sulforaphane does synergistically induce the HO-1 protein when combined with Cu(II). The mechanism of this synergy is explored.

      

Synthesis of a Lemonose Derivative

Alicia Briegel
Advisor: Dr. Robert Giuliano

Lemonose is a sugar unit that is part of the natural product lemonomycin, which has shown activity against strains of bacteria such as methicillin-resistant Staphylococcus aureus (MRSA). A previous study on a class of carbohydrate-containing antibiotics, anthracyclines, showed that changing the functional groups on the sugar unit could change the activity and/or toxicity of the compound. The goal of this work is to synthesize 2,4,6-trideoxy-4-amino-3-C-methyl-L-lyxohexopyranose, a derivative of lemonose (shown below). The key synthetic challenge currently under investigation is formation of the cis amino alcohol. 

Tuesday, November 12, 2013

4:30pm – 5:20pm

 

Mendel 213

Mendel Science Center

The Public Is Invited To Attend

Summer Undergraduate Research Program at Gerstner Sloan-Kettering

The Gerstner Sloan-Kettering Graduate School of Biomedical Sciences sponsors a 10-week research program for outstanding undergraduate students who are interested in pursuing a career in biomedically related sciences.  Students in the program will have the opportunity to interact with faculty, posdoctoral fellows, and graduate students.  Attend weekly luncheon/seminar series with presentations by faculy.  Attend skills/development workshops, such as presentation skills, interview skills, etc.  Program begins on the first Monday in June and runs for 10 consecutive weeks.  Students who are accepted into the program will be offered a stipend of $4,000 and housing.   Four exceptional students will be selected and named "Rubin and Sarah Shaps Scholars".  The deadline for submission of all application materials is February 1.  Applicants will be notified of a decision by March 15.  For eligibility requirements, further information and to apply, please go to:  www.sloankettering.edu

Atlantis Project Study Abroad - 3 week January Program and 5 week Summer Program

PRE-HEALTH?  Intern at a European hospital in the North Atlantic!  The Atlantis Project brings pre-health undergraduate tudents for 5-week summer programs and a 3-week January program in the Canary Islands (Spain) and the Azores Islands (Portugal).  Atlantis Fellows intern at local public hospitals, see the European healthcare system from the inside, improve language skills, participate in a bioethics seminar and contribute to the community by teaching English to local residents - all of this in some of the most beautiful places on earth.   Deadlines:  3-week January 2014 session - Apply online by November 17, 2013; 5 week Summer 2014 sessions:  3 application rounds:  December 1, February 2, and March 2.  For further information and to apply, please go to:  www.atlantis-project.org

American Chemical Society's SCI Scholars - Summer 2014 Internships for Undergraduates

The American Chemical Society is pleased to announce the fifth year of the summer internship program, SCI Scholars, for chemistry and chemical engineering undergraduates.  Exceptional sophomore and juniors with a GPA of at least 3.5 and who are majoring in chemistry or chemical engineering are encouraged to apply.  Thirty Five scholars will be chosen for internship positions in the summer of 2014.  SCI Scholars will reeive $6,000-$10,000+ for a ten-weeek internship.   Students will be awarded a certificate and an additional $1,000 which can be used for any purpose, such as participation at an  ACS or AIChE meeting.   Applications are due December 14, 2013.  Interested students should visit www.acs.org/sci to fill out an application and get more information. 

Virginia Tech Summer Undergraduate Research Program

Virginia Tech, in conjunction with the NSF, is offering another opportunity for undergraduates to participate in research while earning $7,000 during summer 2014.  Applications are being accepted in both the sciences and engineering on the topic of Polymeric Nanostructures for Delivering Drugs and Imaging Agents.  Application review will begin on February 1, 2014.  The Program runs from May 20th until August 1, 2014.  Applicants should be rising juniors and seniors (preferred) U.S. Citizen or Permanent U.S. Resident.  For further information and to apply, please go to http://www.mil.vt.edu/SURP

The CHOP Research Institute Summer Scholars Program (CRISSP)

The Children's Hospital of Philadelphia Research Institute is pleased to announce the return of The CHOP Research Institute Summer Scholars Program (CRISSP).  CRISSP is a 10-week competitive summer internship program for undergraduate students interested in careers in the biomedical sciences.  The internship is designed to provide students with theoretical knowledge, practical training in academic research, and critical exposure to pediatric-focused career trajectories under the direct mentorship of CHOP faculty.  Full time immersion in a lab or research group allows interns to experience science and discovery first hand.  A stipend will be provided.  The program runs June 2 to August 8, 2014.  Additional information is available on our website:  http://www.research.chop.edu/programs/crissp/   CRISSP is a great opportunity for Villanova University students.  Students with competitive grades and career goals consistent with a future in biomedical research are encouraged to apply.  Applications will be open in November.  Up to 25 students will be accepted. 

Match Education & Match Teacher Residency Fellowship Programs

Match Education is recruiting all majors.   Candidates do not need to have a background in education.    We seek candidates with strong content backgrounds - math, science, English, history, etc., and those who share our passion for social justice and education reform.   Match Education is a non-profit education foundation based in Boston and is looking for Villanova University grads to come tutor our students in Boston, MA.  Match Corps and Match Teacher Residency are one-year urban education fellowship programs that pair recent college graduates from top universities with a small caseload of Match students whom they work with in small group on 1-on-1 tutorials over the course of each day, providing close academic support and building relationships to guarantee the academic success of their Match students.  Teacher Residents participate in a teacher training program that prepares them to teach in "No Excuses" urban classrooms.  All details about the programs can be found here:  http://www.matcheducation.org/apply.   If you have any questions, please email recruiting@matcheducation.org 

2014 Summer Research at MIT - Amgen-UROP Scholars Program

Now entering its eighth year, the Amgen-UROP Scholars Program invites undergardatues to participate in faculty-mentored summer research in MIT laboratories.  This intensive nine-week program focuses on cultivating and supporting partnerships between MIT faculty and undergraduates in the areas of science and biotechnology.   Students indicating a strong desire to engage in research collaborations within these areas will be selected from colleges and universities from around the U.S., as well as the MIT undergraduate population. 

The 2014 Summer Program runs from June 9th to August 8th.   Apply online between November 1, 2013 to February 3, 2014: www.amgenscholars.com; Admissions decisions:  Early March 2014;  July 2014 (dates TBA):  Mid-summer symposium at UCLA in Los Angelese, CA  (travel expenses; room & board are covered). 

Amgen-UROP Scholars working 40 hours per week for the nine-week period will earn $4,700, at an hourly wage of $13.05.  In addition, an $800 meal allowance and on-camus housing is provided to all Scholars.  Travel to and from MIT for the beginning and end of the Program is covered for visiting (non-MIT) students.  Must be a U.S. citizen or U.S. permanent resident; undergraduate students enrolled in accredited four-year colleges or universities in the U.S., Puerto Rico or other U.S. territories; and Sophomores (with four quarters or three semesters of college experience), juniors or non-graduating seniors (who are returning in the fall to continue undergraduate studies).  U.S. Program applicants must also have:  a cumulative grade point average of 3.2 or above; and an interest in pursuing a Ph.D. or M.D.-Ph.D.   To learn more about the MIT Amgen-UROP Scholars program and how to apply please visit:   www.amgenscholars.com

University of Pennsylvania Axalta Distinguished Lectures

University of Pennsylvania announces the Axalta Distinguished Lectures, featuring Dr. Robert Langer, David H. Koch Institute Professor (MIT)   Biomaterials and Biotechnology:  From the discovery of the first angiogenesis inhibitors to the development of controlled drug delivery systems and the foundation of tissue engineering.  This even will take place on Thursday, October 24, 2013 at 3:30 pm Room 102 Department of Chemistry, School of Arts and Sciences.  For information, call 215-898-9722.

Lehigh University Open House

Department of Chemistry, Lehigh University is pleased to announce the College of Arts and Sciences at Lehigh University is hosting an Open House Event on Saturday, October 16 from 9:30 am - 2 pm.  Students can use the following link to register:  https://cas.cas2.lehigh.edu/content/open-house.   The Chemistry Department will be hosting a concurrent poster session.   Students who attend the event will meet with faculty and current graduate students to learn about graduate studies in chemistry and biochemistry at Lehigh.   Light refreshments will be served.  The $75 application fee will be waived for anyone who attends this even and applies for graduate studies in the Chemistry Department.  Please email JoAnn DeSalvatore (jmd207@lehigh.edu) with any questions.   http://www.lehigh.edu/chemistry

BRIDGE Society SCIENCE Mentoring & Networking Event on Wednesday, October 2nd

You are invited to the BRIDGE Society SCIENCE Mentoring & Networking Event on Wednesday, October 2nd at 5:00 pm in the Garey Hall Cafe.

Meet alumni and professions who will be sharing advice regarding research, graduate and medical school, and employmnet in scientific and non-scientific fields.   The following organizations are represented:  DuPont, Johnson & Johnson, GenoSpace, University of Pennsylvania Medical School, American Chemical Society, Jefferson Medical college, UnitedHealthcare, U.S. Environmental Protection Agency and more.

RSVP:  https://sp.artsci.villanova.edu/ous/Lists/BRIDGE%20Events/NewForm.aspx  For further information or if you have any questions, please contact Karen Graziano, J.D. 610-519-7427, karen.graziano@villanova.edu

The Stowers Summer Scholars Program

The Summer Scholars Program at the Stowers Institute for Medical Research offers students with a passion for science the extraordinary opportunity to join a laboratory and immerse themselves in a research topic full-time over a ten-week period to explore a potential career in science.   For more information and deadline, contact Ana Pedraza, Summer Scholars Program Coordinator - 816.926.4400   studenttrainingprograms@stowers.org